Curious Conversations, a Research Podcast

"Curious Conversations" is a series of free-flowing conversations with Virginia Tech researchers that take place at the intersection of world-class research and everyday life.
Produced and hosted by Travis Williams, assistant director of marketing and communications for the Office of Research and Innovation, episodes feature university researchers sharing their expertise, motivations, the practical applications of their work in a format that more closely resembles chats at a cookout than classroom lectures. New episodes are shared each Tuesday.
If you know of an expert (or are that expert) who’d make for a great conversation, email Travis today.
Latest Episode
Bryan Hsu joined Virginia Tech’s “Curious Conversations” to talk about bacteriophages, commonly called phages. He explained their role in the gut microbiome, their potential in phage therapy, and the potential as a tool against antibiotic resistance. Hsu also broke down how phages interact with bacteria, their dual nature as both beneficial and harmful, and the innovative ways researchers are engineering phages for therapeutic use.
(music)
Travis
Currently your body is full of bacteriophages. If this is the first time you've learned this, I apologize that it had to be in this setting. But I have good news for you. Bryan Shue is an expert in this very topic and was kind enough to join me on the podcast to explain what these things are and how they might actually be beneficial to our health.
Bryan is an assistant professor in the Department of Biological Sciences and an affiliate of the Freeland Life Science Institute. His research broadly focuses on using an interdisciplinary approach towards understanding and remodeling gut microbiota, with a special focus on discovering new phages and genetically engineering them to do good things for us. So Brian and I talked a little bit just about what phages are, how long we've known about them, and we got into what they do and don't do inside our guts. We also talked about what we're talking about when we're even saying the word guts because frankly, I wasn't really sure. explained to me some of the positive uses that he thinks phages might be able to do specifically related to antibiotic resistant bacteria and also the delivery of drugs in our guts. He shared a little of how he got into this field, why it gives him hope for the future and not to spoil anything, but we wound down the conversation talking about the importance of poop in this whole process. Be sure to follow, rate and or subscribe to the podcast.
I'm Travis Williams and this is Virginia Tech's Curious Conversations.
(music)
Travis
I know you've done a lot of work around this topic of bacterial phages. So I think that's just a great place to start. What are bacterial phages?
Bryan
Yeah, bacteriophages, sometimes people call them phages, which I'll do now because it's just shorter and easier. These are viruses that only affect bacteria. So they're all over the place. Everywhere where there's bacteria, there's probably a bacteriophage. Most people will know about phages because of phage therapy. So there is this interest in using phages to kill bacteria as an antimicrobial especially for bacteria that are maybe antibiotic resistant. But because we can find them everywhere, they're kind of ecologically entrenched with bacteria. you you say, people say that your gut microbiome, sometimes you're more bacteria, bacterial cells and human cells. There are just as many phages in the gut as bacteria. And so what we're trying to figure out is what is the significance of these phages? to bacteria and to kind of the host environment that they're in. For example, us, if they're in the gut microbiome. And that's an area that's not super well understood. That's an area that people are trying to get into and trying to understand. And there could be some cool things, but we just don't know them yet.
Travis
So do I have phages in my gut right now?
Bryan
Yeah, you're full of them.
Travis
And I hear people ask this all the time and my son who's six asked me this question the other day. He said, what is my gut? So what are we talking about when we say the gut? I know that's a simple word. use it a lot of times, but I'm curious. Is it my stomach? Is it my intestines? What is it?
Bryan
It's all of those things. mean, it's the whole gastrointestinal tract and there as you like, you're basically a big meat tube, right? The inside of you is where the digestion happens, right? So, so then you eat food and it starts degrading your mouth, breaks it down, stomach breaks it down even further, your small intestine starts absorbing the little pieces of the things that you broke down. And then eventually that massive food that you ate turns into poop, right? And so along this tube that you have, you have a microbiome bacterial components, viruses that change for the whole duration of that tube, because you have different things available. And you as the body, your body itself has different things that can be provided to those things in your in your intestinal tract. So when people talk about a gut, it's usually just this short term, this a quick way of saying your whole GI tract, but most of the microbiome stuff that you might be thinking of probably happens in your lower GI tract.
Travis
Well, how long have we known about phages?
Bryan
long time, like more than 100 years. So we knew about bacteria before that obviously. But when we first learned about phages, people knew that they killed bacteria and they thought of them as antimicrobial. They thought they were exciting because this would be a new way of killing bacteria. And they came around a little bit before, but right around the same time as antibiotics. But because, you know, antibiotics took off, phages became less exciting as antimicrobial. But people, scientists at least, have been studying phages for a long time and they, there were means for understanding genetic transfer. So how genes can transfer between species or between cells. And so they had been of, you know, a lot of scientific interest for a while.
Travis
How are we able to leverage these to help maybe fight against bacteria? Because if they fight bacteria and I have them, it seems like obviously that's a bad question.
Bryan
you're asking a good great question because people always wonder about the anti the the bacterial killing effect right for phage therapy there that's the primary thing people are interested in is can we find or engineer phage to be a better killer of their targeted bacteria right phages are pretty specific and that they like certain species so that's one of the reasons why people are interested in phages now is that you can potentially kill a pathogen without affecting the rest of your gut microbiome, for example. So one way doing engineering or isolating from wastewater and things like that, people will try to see which phage can we isolate from the environment or generate has the best killing properties. And, you know, using these phages in phage therapy, that's a whole nother challenge. Because if you look at the role of phages, in the ecological environments that end up coexisting with bacteria. So it's optimal to not necessarily kill all of their bacterial hosts. I always like to think of things in more of like a macroscopic environment, right? If you think of lions, right? Trying to kill gazelle or something like that. I don't know if they're actually in the same environment. The ecology of my department will kill me. But a predator killing a prey, is it to the predator's benefit to kill all the prey? And right in the way you could if you deploy lions as anti gazelle therapy, I mean, what you probably is going to end up what's probably going to end up happening is that you have this predator prey kind of coexistence that happens. So with bacteria and bacterial phages, there's also this coexistence that occurs where phages propagate on their bacterial hosts. But then sometimes they deplete whatever bacteria are available to them. And then those other bacteria that are able to hide really well will survive. And then the phages kind of disappear a little bit until those bacteria reveal themselves again. And so they end up having this back and forth between each other. And there's also genetic elements that allow bacteria to be resistant to the phages and phages can counteract that resistance and so on. So there's multiple levels of this coexistence that occurs.
Travis
Yeah, is there any way to know which, is there certain types of bacteria that they target versus they just kind of live in peace with?
Bryan
Yeah, well, it's hard actually. We don't, have a general idea from, you know, doing, doing sequencing of the bacteria phages that are in the environment. You can do some host assignments, but usually it's not to this level of specificity that's needed to really precisely know which bacteria get infected by the phage. But there are different kinds of phages. There are phages that are virulent or follow a lytic life cycle. That's where every successful infection leads to bacterial cell death and the release of new phages. So that's like a lytic life cycle. There's also this lysogenic life cycle where a phase can affect the bacteria and then also integrate its genome into the bacterial genome and kind of hang out for a while until they feel the time is right. then they jump into the lytic life cycle where they make progeny, phage, lysate, bacteria that release those phage.
Travis
That was actually my next question was like, what about on the phage side of things? Can we figure that part out a little bit better? And it sounds like that maybe we have.
Bryan
Yeah, we're learning a lot about how phages interact with the bacteria in our life cycle and what are phages doing. But there's still so much more to learn. Every time we learn a little bit of something that opens a door for several new things to try to figure out.
Travis
Yeah. Do we know some of these phages that are more active and are more proactive against certain bacteria? Do we know how to use these to help make us feel better in general yet?
Bryan
We're trying. We know that phages have specific effect on their bacterial hosts. Now, bacteria don't live alone. They live in communities, sometimes with hundreds of other different kinds of bacterial species, especially in the gut. So if you introduce a phase that targets one bacteria, how does that affect the entire community? And that is not well understood. You can think that you have a way of altering the bacterial community if you provide enough phages. But to predict that is a little tough because everyone has, you know, different gut microbiome. They have different bacterial communities in their gut. They also will have different phage communities there as well. So if you introduce new phages, how does that affect that community? How does that reshape your gut microbiome? Well, we can try to predict things, but it's not always going to be totally predictive. So there's other ways of, there's, think we, you connected with me to talk about that mouse model that we developed, right? But there's also that we published something earlier, which was using a lytic phage or a virulent phage and engineering it to produce proteins, therapeutic proteins. The idea being with this coexistence, where a phage won't affect a bacteria and lyse that bacteria it can, we can reprogram that phage to produce a therapeutic protein so that it can get released with the progeny phage. and being in directly in the gut microbiome, that's a way of delivering, you know, therapeutic proteins. So we've been able to, produce a few different kinds of proteins, ones like a marker protein. So you can just see where it is. And the other things are things that inhibit, proteases that are associated with IBD or a protein that when it's broken down mimics a satiety hormone. And so when we give mice a high fat diet, when we have this engineered phase, gain way less weight than a mouse that has the non-engineered phase or no phase at all. So there are some ways to leverage through genetic engineering, know, leverage the natural relationship that bacteriophages have with their bacteria for therapeutic function. But then there's also other ways of trying to modulate the gut microbiome as a whole, that we're still learning about what are the consequences of that. Because what I mentioned of the community living in coexistence, everyone having a different gut microbiome. So the predictive ability there is going to be a little bit more difficult.
Travis
I'm curious, what would you use a therapeutic protein for?
Bryan
Well, if you watch TV and you see all these pharmaceutical advertisements for things to treat whatever diseases, those are usually protein therapeutics. You know, like monoclonal antibody for targeting something or you have peptides, you know, like GLP-1 agonists, have Wigovia and all this kind of stuff. Those are protein or peptide based. So, The thing about oral, like when you go to the supermarket or you go to CVS or something and you have a headache and you go get Advil or Tylenol or something like that. You can take it and swallow it and then it works that way, right? Because it's a small molecule, it doesn't get degraded in your stomach and then it gets released in your intestines and the small molecule can be absorbed really easily. then so that's an easy way to take things, things that are proteins are really tough to administer orally because your body is built to break down biological materials, right? Because you eat food, you eat proteins, you eat these kinds of things, your body's built to digest that stuff. And so the likelihood of those things that you eat or the biologics you take orally passing through your stomach is really low because it's probably gonna get degraded. that has generally been a challenge. And so if we use phages and then replicate on your gut bacteria to produce those proteins that normally wouldn't be orally available.
Travis
I'm curious what the potential is for phages, especially related to this kind of rise in antibiotic resistant bacteria, because I see that a lot being publicized. I see it a lot in the news. It's a major concern of a lot of people. It's the reason why my wife is like, make sure you finish all your antibiotics all the time now. Do you think the phages may provide some answers to maybe that problem now or in the future?
Bryan
It's tough because bacteria like to not be killed by any means, So whether by antibiotic or any other means. for antibiotics, know, antibiotics work usually by specific mechanisms where they will target some feature of a bacteria that the bacteria needs, right? And then bacteria replicate so rapidly that they can, like a large fraction will die, but some others will have had this adaptation through mutation to where they're not susceptible anymore to that particular antibiotic. And then you can choose another antibiotic or another one. And then so when we run out of antibiotics, so what's the choice now? Well, know, phages might be that choice. They have a way of killing bacteria that is different than antibiotics, and they can replicate on the bacteria. But just like bacteria developing resistance to antibiotics, bacteria can develop resistance to phages. So there's think as an alternative, if you were the one that is dying and you need a way to get rid of this bacterial infection, antibiotics don't work. Phages are fantastic thing to look into. But they are not. Well, I shouldn't say this because you're going to post it, but they they may not be the ultimate solution because bacteria on a whole can develop resistance to phages as well. Right. So they don't, I don't think that they're going to be replacing antibiotics, but for the individual or individuals that are in desperate need of some kind of therapeutic, you have to look at all options, including phages.
Travis
So maybe not the end-all be-all solution to get rid of all illness, but maybe this is another tool that we put in the tool belt to fight against some of these tricky bacteria. Are there good and bad phages or is most of their work resulting like a positive thing? Yeah.
Bryan
Well, okay, so the positive thing we don't know about that's actually stuff that we're my lab is trying to study. There, you can say that they're doing neutral stuff, maybe. It's just not really, really well known, right? I think they're doing positive stuff. I don't, we're building evidence to show that they're doing positive stuff. So I can't tell you definitively yet, but I think we have some good preliminary evidence that they are. We do know that they're doing negative stuff, though, some of them. So things like pathogenic E. coli sometimes can have these temperate phages that have integrated into their genome. And they're dormant usually. But then every once in a while, they'll decide, oh, I want to go through the lytic life cycle. they excise or pull their phage genomes out of the bacterial genome, replicate, make new phages. lyse the cell and release these progeny phages that can go and infect new bacteria. So that sucks for the bacteria. So it doesn't affect us. But those prophages or those phages that are integrated into the bacterial genome also have these genes that produce toxins. So they only release these toxins when they go through the lytic life cycle. So things like sugar toxin, cholera toxin, these kind of toxins are produced and released when those phages lyse those bacteria. And that's why in some cases when you have an enteric infection with E. coli, the doctors say don't take antibiotics. It's because certain types of antibiotics can induce these phages to pop out and produce toxins. So actually it will make your infection worse.
Travis
So it sounds like we just really need to understand more about these things.
Bryan
I think so too. Yeah, yeah,
Travis
How did you get into this line of work and did you want to study bacteria and the things that happen in our body and our guts?
Bryan
I think it's weird because sometimes it's like a circumstance of your situation. So I was a chemical engineer and a material scientist as an undergrad. So I had engineering degrees. And then I did research in a chemistry lab, something like physical chemistry, studying catalysis. The thing that your car does, your catalytic converter, you have all these beads of precious metals. And then the reason they're there is because they convert the output gas of your engine car engine into like water and stuff and CO2. So I used to study how those reactions happen on the surfaces. And then I realized that when I went to grad school, that I kind of wanted to do something more biologically related. And then so I was technically a chemist in in my PhD. program. And then I was making thin films that release drugs, things that will kill bacteria, for example, on implants, right to prevent implant related infections. And then when I finished my PhD, I realized, you know, I know nothing about bacteria, the things that I'm trying to target. So then I did a postdoc in systems or synthetic biology with the gut microbiome and there happened to be a position open in the gut microbiome area. And then I wanted to work in something different that not everyone will be working on because I knew that I knew nothing about whatever I was starting to do. So I wanted like a longer runway to catch up. So I started working on phages because they weren't too hot in terms of research-wise. We're getting more exciting. Things are picking up. People are getting more interested. So yeah, during my postdoc, I was working on that and then I applied for broccoli jobs, came to Virginia Tech and then started my lab, mostly working on bacteriophages. But then we have another part of my lab that's working on biomaterials for women's health. So I still keep a little bit of my engineering in my research.
Travis
That's awesome. sounds like you kind of went from maybe studying how don't know, it sounded like engines and cars work to studying how the engines that we are.
Bryan
Yeah, everywhere needs, everything needs more investigation, I think, to advance in society.
Travis
guess I'm curious, in this space, what gives you hope?
Bryan
Well, there's a hope of opportunity, you know, hope in the unknown, because we're learning so much about what is there, but we don't know how the things are happening or what the consequences are of those things for health, for example. So learning about these inner mechanisms of things you probably would never have thought of, right? most people never think about bacteriophages, right? Opens a door for new opportunities of understanding how to benefit health. You know, maybe these phases are doing something exciting that we didn't know and then we can use this therapeutically. It also opens opportunities for other people to do innovative things, which is, you know, once these ideas become available, other more creative people or intelligent people can devise something that is exciting, know, therapeutically, commercially, environmentally, all kinds of reasons. increasing this knowledge out there, I feel like opens a larger door for new opportunities for people to get excited in.
Travis
Well, I think that does sound very helpful, especially seeing how you're studying things that are just like running all through me. So I would look for you to better understand that to help you.
Bryan
Yeah, the best thing about studying the gum microbiome is so easy to study. You just collect poop and you're just non-invasive,
Travis
I hope so.
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Travis
And thanks to Brian for helping us better understand phages and the work that he and his colleagues are doing to help unlock the potential they may have to benefit our health. If you or someone you know would make for a great curious conversation, email me at Traviskw at bt.edu. I'm Travis Williams and this is Virginia Techs. Curious Conversations.
(Music)
About Hsu
Bryan Hsu is an assistant professor in the Department of Biological Sciences and an affiliate of the Fralin Life Sciences Institute. His research broadly focuses on using an interdisciplinary approach towards understanding and remodeling the gut microbiota with a special focus on discovering new phages and genetically engineering them for anti-bacterial and anti-virulence applications.
Past Episodes
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General ItemBacteriophages' role in the gut with Bryan Hsu
Bryan Hsu discusses bacteriophages, their role in gut health, and their potential in addressing antibiotic resistance through phage therapy.
Date: May 12, 2025 - -
General ItemMake Sense of Economic Climates with David Bieri
David Bieri discusses the human side of economics, the value of historical context, and the importance of rethinking economic ideas and institutions.
Date: May 05, 2025 - -
General ItemThe Magic of 'The Magic School Bus' with Matt Wisnioski and Michael Meindl
Matt Wisnioski and Michael Meindl explore how “The Magic School Bus” shaped science, education, and entertainment.
Date: Apr 28, 2025 - -
General ItemUsing Virtual Reality to Explore History with Eiman Elgewely
Eiman Elgewely joined Virginia Tech’s “Curious Conversations” to talk about her work using virtual reality and the principles of interior design to explore historical spaces.
Date: Apr 21, 2025 - -
General ItemUltra-Processed Foods with Alex DiFeliceantonio
Alex DiFeliceantonio discusses ultra-processed foods, their health impacts, and how dopamine influences food choices in Virginia Tech’s “Curious Conversations.
Date: Apr 14, 2025 - -
General ItemTechnology’s Impact on the Appalachian Trail with Shalini Misra
Shalini Misra explores how digital technologies are changing the Appalachian Trail, balancing tradition, accessibility, and environmental preservation.
Date: Apr 07, 2025 - -
General ItemThe Dangers of Gaze Data with Brendan David-John
Brendan David-John discusses the use of gaze data in virtual and augmented reality, including privacy concerns and current mitigation research.
Date: Mar 31, 2025 - -
General ItemCommunity Dynamics During and After Disasters with Liesel Ritchie
Liesel Ritchie discusses how sociology helps explain community resilience in disasters, the role of social capital, and the importance of local relationships.
Date: Mar 24, 2025 - -
General ItemDrone Regulation, Detection, and Mitigation with Tombo Jones
Tombo Jones discusses drone regulations, safety, and counter UAS strategies, highlighting Virginia Tech’s role in advancing uncrewed aircraft systems.
Date: Mar 17, 2025 - -
General ItemPublic Perception of Affordable Housing with Dustin Reed
Dustin Read discusses public perceptions of affordable housing, the role of profit status, and how development size impacts community support.
Date: Mar 10, 2025 - -
General ItemUnpacking the Complexities of Packaging with Laszlo Horvath
Laszlo Horvath discusses packaging design complexities, including affordability, sustainability, and the impact of tariffs and supply chain disruptions.
Date: Mar 03, 2025 - -
General ItemEngineering Safer Airspace with Ella Atkins
Ella Atkins discusses air travel safety, VFR vs. IFR challenges, recent collisions, and how technology and automation can enhance aviation safety.
Date: Feb 24, 2025 - -
General ItemCancer-Fighting Bubbles with Eli Vlaisavljevich
Eli Vlaisavljevich discusses histotripsy, an ultrasound therapy for cancer, its mechanics, clinical applications, and future directions in treatment.
Date: Feb 17, 2025 - -
General ItemExamining the ‘5 Love Languages’ with Louis Hickman
Louis Hickman discusses ‘The 5 Love Languages,’ their impact on relationships, research findings, and the role of personality, self-care, and adaptability.
Date: Feb 10, 2025 - -
General ItemThe Behavior and Prevention of Wildfires with Adam Coates
Adam Coates explores the factors behind California wildfires, fire behavior science, urban challenges, and the role of prescribed burning in prevention.
Date: Feb 03, 2025 - -
General ItemComputer Security in the New Year with Matthew Hicks
Matthew Hicks discusses evolving computer security threats, AI-driven risks, and practical tips to stay secure in 2025.
Date: Jan 27, 2025 -
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General ItemInternet of Things Safety and Gift Giving Tips with Christine Julien
Christine Julien joined Virginia Tech’s “Curious Conversations” to talk about the Internet of Things (IOT), exploring its definition, potential vulnerabilities, and the implications of using smart devices, especially for children. Julien stressed the importance of security and privacy when using IOT devices, particularly during the gift-giving season and shared insights on navigating these complexities with an aim of balancing the enjoyment and security.
Date: Dec 09, 2024 - -
General ItemNeurodiversity and the holidays with Lavinia Uscatescu and Hunter Tufarelli
Lavinia Uscatescu and Hunter Tufarelli joined Virginia Tech’s “Curious Conversations” to talk about the importance of understanding and accommodating neurodivergent individuals in various environments, particularly social gatherings during the holiday season. The pair shared the impact environmental factors can have on neurodivergent individuals, as well as the significance of predictability and communication in social settings. As a person with autism, Tufarelli also shared her first-hand experiences and the importance of embracing self-care.
Date: Dec 02, 2024 - -
General ItemAI and Better Classroom Discussions with Yan Chen
Yan Chen joined Virginia Tech’s “Curious Conversations” to talk about the use of artificial intelligence to enhance teaching and peer instruction in classrooms. Chen believes one potential use for AI, specifically large language models, is to monitor and analyze peer interactions in real-time. He shared the platform he and colleagues have created to do this, called VizPI, which aims to provide instructors with insights and recommendations to create a more engaging and personalized learning environment for students.
Date: Nov 25, 2024 - -
General ItemForest Health and Natural Disasters with Carrie Fearer
Carrie Fearer joined Virginia Tech’s “Curious Conversations” to talk about forest health in the wake of natural disasters. She explained how storms and disturbances affect forest ecosystems, the importance of human interaction in promoting healthy forests, and the opportunities for restoration following catastrophic events. She also emphasized the significance of native species and the role of decomposition in maintaining forest health.
Date: Nov 18, 2024 - -
General ItemSubduction Zones, Earthquakes, and Tsunamis with Tina Dura
Tina Dura joined Virginia Tech’s “Curious Conversations” to talk about subduction zones, particularly the Cascadia Subduction Zone, earthquakes and tsunamis. She explained the mechanics of earthquakes, and how the geological record and fossilized algae are helping researchers better understand past occurrences and predict future ones. Dura emphasized the importance of translating scientific research into actionable information for the public, especially regarding tsunami preparedness and community resilience.
Date: Nov 11, 2024 - -
General ItemTurning old Plastic into Soap with Guoliang “Greg” Liu
Guoliang “Greg” Liu joined Virginia Tech’s “Curious Conversations” to talk about his journey in sustainability, focusing on the innovative process of converting plastic waste into soap. He shared insights on the challenges of controlling the chemical processes involved, the types of plastics used, and the potential for creating both liquid and solid soap products. He emphasized the importance of sustainability in the detergent industry and expressed hope for future commercialization of his work.
Date: Nov 04, 2024 - -
General ItemEmerging Technologies and Entrepreneurship with James Harder
James Harder joined Virginia Tech’s “Curious Conversations” to talk about entrepreneurship and emerging technologies, specially highlighting the Department of Computer Science’s initiative, CS/root. Harder shared his belief that the entrepreneurship process can be learned and applied to various novel ideas and the ways the program hopes to teach and support it, as well as the role it will play in putting emerging technology in more people’s hands.
Date: Oct 28, 2024 - -
General ItemAI and Emergency Management with Shalini Misra
Shalini Misra joined Virginia Tech’s “Curious Conversations” to talk about how artificial intelligence (AI) might be used in the field of emergency management. She shared some of the different ways AI is currently being used and the concerns she’s heard from emergency managers. Misra also talks about the steps she believes will be necessary for the technology to reach its full potential in this field.
Date: Oct 21, 2024 - -
General ItemFemale Leaders of Nations and the US Presidency with Farida Jalalzai
Farida Jalalzai joined Virginia Tech’s “Curious Conversations” to talk about the state of female leadership globally, with a focus on the United States. She shared how she believes the U.S. compares to other nations in terms of female political representation, the unique challenges women face in the U.S. political landscape, and the impact of gender roles on women's leadership opportunities. She also shared the insights she gained through her research of female leadership during the COVID-19 pandemic.
Date: Oct 14, 2024 - -
General ItemAI and Securing Water Systems with Feras Batarseh
Feras Batarseh joined Virginia Tech’s “Curious Conversations” to discuss the intersection of water systems and technology, specifically focusing on aspects of artificial intelligence (AI). He shared the importance of using AI to predict and prevent water quality issues, such as high turbidity, and highlighted the need for water systems to become more intelligent and cyber-secure.
Date: Oct 07, 2024 - -
General ItemAlcohol Use and Intimate Partner Violence with Meagan Brem
Meagan Brem joined Virginia Tech’s “Curious Conversations” to discuss the intersection of alcohol use and intimate partner violence, highlighting the importance of understanding the causal relationship between the two. She debunked common myths, identified current knowledge gaps, and shared insights from ongoing studies. She also described the unique challenge of understanding these topics as they relate to LGBTQ+ populations and shared possible interventions on both societal and individual levels.
Date: Sep 30, 2024 - -
General ItemBrain Chemistry and Neuroeconomics with Read Montague
Read Montague joined Virginia Tech’s “Curious Conversations” to talk about the role of dopamine and serotonin in learning, motivation, memory, mood, and decision-making. He discussed his research on measuring dopamine and serotonin dynamics in the brain in real time using electrodes in epilepsy patients and explained the role neuroeconomics are playing in that research.
Date: Sep 23, 2024 - -
General ItemThe Future of Wireless Networks with Lingjia Liu
Lingjia Liu talks about the future of wireless networks.
Date: Sep 16, 2024 - -
General ItemThe Mung Bean and Reducing Hunger in Senegal with Ozzie Abaye
Ozzie Abaye joined Virginia Tech’s “Curious Conversations” to talk about her work using the mung bean to diversify the cropping system, empower farmers, and reduce hunger in Senegal, Africa. She explained why the mung bean is a good fit for that region, the process by which she began to share it with farmers, and the collaborations she’s utilized to expand it across the country. She also shared what some of the challenges were in developing recipes across cultural lines.
Date: Sep 10, 2024 - -
General ItemCurbing the Threat of Invasive Species with Jacob Barney
Jacob Barney joined Virginia Tech’s “Curious Conversations” to talk about invasive species, their impact on native species, and the challenges of managing them. He explained the history and terminology of invasive species, their economic and ecological consequences, and the interdisciplinary approach to addressing the problem. Barney also highlighted practical steps individuals can take to prevent their spread.
Date: Sep 02, 2024 - -
General ItemMaking Motorcycle Riding Safer Around the Globe with Richard Hanowski
Richard Hanowski joined Virginia Tech’s “Curious Conversations” to talk about harnessing research to help make motorcycle riding safer in low- and middle-income countries. He shared the difference in riding culture in those areas as opposed to the United States and explained how his team is utilizing some of the Virginia Tech Transportation Institute’s pioneering technology to help increase rider safety.
Date: Aug 27, 2024 - -
General ItemThe Evolution of Political Polling with Karen Hult
Karen Hult joined Virginia Tech’s “Curious Conversations” to chat about the history and evolution of polling, methods used in modern polling, and how politicians and the average person can interpret poll results. The conversation highlights the importance of probability sampling and inferential statistics in generating accurate poll results, as well as the need for critical thinking when consuming poll results.
Date: Aug 20, 2024 - -
General ItemNavigating Back-to-School Emotions with Rosanna Breaux
Rosanna Breaux joined Virginia Tech’s “Curious Conversations” to chat about the challenges and emotions children may experience during the transition back to school. The discussion includes red flags to look for, as well as coping skills and support parents and caregivers can provide to help their children navigate the school year. The conversation touches on the impact of recent bans on students having individual smart devices in schools.
Date: Aug 05, 2024 - -
General ItemGeologic Carbon Sequestration with Ryan Pollyea
Ryan Pollyea joined Virginia Tech’s “Curious Conversations” to talk about geologic carbon sequestration, which is the process of permanently storing carbon dioxide (CO2) thousands of feet below the Earth’s surface. Pollyea explained what types of rock this is currently known to work with, the efforts he and his colleagues are taking to expand this to other geologic regions, and the potential impact that could have for the environment and economics.
Date: Jun 04, 2024 - -
General ItemVeterans and Mass Incarceration with Jason Higgins
Jason Higgins joined Virginia Tech’s “Curious Conversations” to talk about the intersection of United States military veterans and mass incarceration and his book, “Prisoners After War: Veterans in the Age of Mass Incarceration.” He shared what led him to work at this intersection, some of the reasons he thinks it’s often overlooked, and factors he believes lead many veterans to being in prison. Having interviewed more than 60 veterans whose service ranged from the Vietnam War to the wars in Iraq and Afghanistan, Higgins also compares and contrasts their reported experiences and shares some of the efforts veterans are undertaking to support each other.
Date: May 28, 2024 - -
General ItemMicroplastics, the Ocean, and the Atmosphere with Hosein Foroutan
Hosein Foroutan joined Virginia Tech’s “Curious Conversations” to talk about microplastics, the ocean, and the atmosphere. He explained what microplastics are and shared recent findings that indicate such waste is somehow making its way into the air around the world. He also described some of the research he’s doing to figure out how this is happening and shared his current theories.
Date: May 21, 2024 - -
General ItemReal Estate Values and Elections with Sherwood Clements
Sherwood Clements joined Virginia Tech’s “Curious Conversations” to talk about the impact real estate values have on the presidential election. He discussed some recent research he was a part of that explored the impact of the “homevoter,” what findings surprised him, and what he thinks the date tells us about the upcoming election.
Date: May 14, 2024 - -
General ItemAI and the Hiring Process with Louis Hickman
Louis Hickman joined Virginia Tech’s “Curious Conversations” to talk about the use of artificial intelligence (AI) during the hiring process. He shared the ways in which AI has long been a part of the process, the findings from his research on AI evaluating automated video interviews, and some tips on how job seekers can leverage the technology to improve their job hunt.
Date: May 06, 2024 - -
General ItemExploring the Human-Dog Relationship with Courtney Sexton
Courtney Sexton joined Virginia Tech’s “Curious Conversations” to talk about the unique relationship between humans and dogs. She shared the origins of the dog-human relationship, how the animals have adapted and become more attune to human needs, and their role in helping researchers learn more about human health.
Date: Apr 30, 2024 - -
General ItemThe Chemistry of Earth History with Ben Gill
Ben Gill joined Virginia Tech’s “Curious Conversations” to chat about piecing together Earth history through a combination of geology and chemistry. Gill explained how studying the cycles of different elements can tell a story and help us better understand the planet’s most pivotal moments, such as mass extinctions. He also shared how studying both the worth and best times of our planet can provide us valuable insights for the future.
Date: Apr 23, 2024 - -
General ItemCircular Economies with Jennifer Russell
Jennifer Russell joined Virginia Tech’s “Curious Conversations” to talk about the concept of a circular economy. She explained that a circular economy is a shift away from the linear economy, which follows a take-make-dispose model, and instead focuses on reducing waste and reusing materials. Russell shared examples of tangible products and industries that can be, or already are, part of a circular economy.
Date: Apr 16, 2024 - -
General ItemThe History of Virginia Tech's Helmet Lab with Stefan Duma
Stefan Duma joined Virginia Tech’s “Curious Conversations” to talk about the history of the Virginia Tech Helmet Lab and the impact it has had on sports-related head injuries. He shared how a military research conference led him to study helmets, as well as the critical role the lab’s relationships with the Virginia Tech football and sports medicine programs have played in advancing this pioneering research. Duma discussed the role of the helmet lab in helping to create a greater awareness about head injuries throughout all sports, and described the helmet shell add-on fans can witness during the football team’s spring game on April 13.
Date: Apr 09, 2024 - -
General ItemThe History of Food Waste with Anna Zeide
Anna Zeide joined Virginia Tech’s “Curious Conversations” to talk about the history of food waste in America and its impact on society and the environment. She shared insights related to several historical turning points and stressed that addressing food waste requires rethinking and integrating food security and waste management systems.
Date: Apr 02, 2024 - -
General ItemThe Dog Aging Project with Audrey Ruple
Audrey Ruple joined Virginia Tech’s “Curious Conversations” to talk about the Dog Aging Project, the largest-known study of dog health which aims to understand the keys to healthy aging in dogs and the risks to their health. She explained what information they are collecting, what it means for dogs, and how it might also be used to better understand human health.
Date: Mar 26, 2024 - -
General ItemAll About Air Pollution with Gabriel Isaacman-VanWertz
Gabriel Isaacman-VanWertz joined Virginia Tech’s “Curious Conversations” to talk about air pollution and its misconceptions. He shared his insights related to how plant and human emissions interact and what that means for our shared environment, as well as how he got into this field of study and his hope for the future.
Date: Mar 19, 2024 - -
General ItemRighting a Wrong Understanding of Newton's Law with Daniel Hoek
Daniel Hoek joined Virginia Tech’s “Curious Conversations” to talk about the recent discovery he made related to Newton's first law of motion. The law is typically translated as “a body at rest remains at rest, and a body in motion remains in motion, at constant speed and in a straight line, unless acted on by an external force." Hoek explains how he became intrigued by the law, the puzzles surrounding it, as well as the misconception that objects with no forces acting on them exist and how Newton's own account contradicts this.
Date: Mar 11, 2024 - -
General ItemMeasuring the Risks of Sinking Land with Manoochehr Shirzaei
Manoochehr Shirzaei joined Virginia Tech’s “Curious Conversations” to talk about the importance of understanding and measuring sinking land, commonly called land subsidence. He shared insights about the use of satellite data in creating high resolution maps, how land subsidence fits into the overall picture of climate change, and how he hopes the information is used by localities.
Date: Mar 05, 2024 - -
General ItemEmerging Technology and Tourism with Zheng "Phil" Xiang
Zheng "Phil" Xiang joined Virginia Tech’s “Curious Conversations” to talk about the intersection of technology and tourism. He shares the significant technological shifts in the tourism industry over the past decade, including the influence of social media and artificial intelligence on trip research and the experience itself.
Date: Feb 27, 2024 - -
General ItemAI and Education with Andrew Katz
Andrew Katz joined Virginia Tech’s “Curious Conversations” to chat about the potential of artificial intelligence (AI) in education. Katz shares his insight related to the applications of AI models, such as chat GPT, in analyzing student responses and providing feedback, as well as the challenges of AI in education and hope it can provide a more individualized education experience.
Date: Feb 20, 2024 - -
General ItemWarm, Fuzzy Feelings and Relationships with Rose Wesche
Rose Wesche joined Virginia Tech’s “Curious Conversations” to chat about the science behind the warm, fuzzy feelings that often accompany a new romance, the transition from infatuation to attachment, and how to maintain intimacy and passion in relationships. She also shared her research exploring the emotional outcomes of casual sexual relationships and provided advice for those in relationships.
Date: Feb 13, 2024 - -
General ItemThe Future of Wireless Networks with Luiz DaSilva
Luiz DaSilva talks about wireless networks and Commonwealth Cyber Initiative's test beds
Date: Feb 06, 2024 - -
General ItemThe Positive Impacts of Bird Feeding with Ashley Dayer
Ashely Dayer joined Virginia Tech’s “Curious Conversations” to chat about her work at the intersection of birds and humans, including a new project that explores the positive impact bird feeding has on human well being and general tips for the hobby.
Date: Jan 30, 2024 - -
General ItemSticking to healthy changes with Samantha Harden
Samantha Harden joined Virginia Tech’s “Curious Conversations” to chat about the science behind developing and keeping healthy habits.
Date: Jan 16, 2024 -
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General ItemScreen Time and Young Children with Koeun Choi
Koeun Choi discusses how media affects young children and shares a project using AI to support early reading development.
Date: Dec 11, 2023 - -
General ItemThe History of Holiday Foods with Anna Zeide
Anna Zeide explores the history of winter holiday foods and how personal traditions surrounding them are created and evolve over time.
Date: Dec 04, 2023 - -
General ItemThe Chemistry of Better Batteries with Feng Lin
Feng Lin explains the chemistry of electric vehicle batteries, current production challenges, and how coal might contribute to future solutions.
Date: Nov 27, 2023 - -
General ItemAI as a Personal Assistant with Ismini Lourentzou
Ismini Lourentzou discusses AI, personal assistants, and her student team’s experience in the Alexa Prize TaskBot Challenge 2.
Date: Nov 20, 2023 - -
General ItemThe Power of International Collaborations with Roop Mahajan
Roop Mahajan discusses how international collaborations have advanced his research on graphene and highlights their broader importance to innovation and scientific progress.
Date: Nov 13, 2023 - -
General ItemDriving around Heavy Trucks with Matt Camden and Scott Tidwell
Matt Camden and Scott Tidwell of VTTI discuss the Sharing the Road program, the research informing it, and practical safety tips for driving near heavy trucks.
Date: Nov 06, 2023 - -
General ItemAutonomous Technology and Mining with Erik Westman
Erik Westman discusses how machine learning and autonomous technologies are shaping the mining industry and how Virginia Tech is preparing students for future careers in the field.
Date: Oct 30, 2023 - -
General ItemAgriculture Technology and Farmers with Maaz Gardezi
Maaz Gardezi discusses the importance of developing agricultural technology in collaboration with farmers and shares insights from an interdisciplinary project focused on innovation at the intersection of agriculture and technology.
Date: Oct 23, 2023 - -
General ItemAI and Healthcare Workspaces with Sarah Henrickson Parker
Sarah Henrickson Parker discusses how artificial intelligence and machine learning is currently being used in some healthcare spaces, and what the potential is for the future.
Date: Oct 16, 2023 - -
General ItemAI and Online Threats with Bimal Viswanath
Bimal Viswanath discusses how the rise in artificial intelligence and large language models has changed the online threat landscape, and a project he’s involved with that aims to mitigate toxic language in chatbots.
Date: Oct 09, 2023 - -
General ItemAI and the Workforce with Cayce Myers
Cayce Myers fields questions on artificial intelligence’s impact on the workforce, regulations, copyright law, and more.
Date: Oct 02, 2023 - -
General ItemSpecial Edition: The GAP Report with Tom Thompson and Jessica Agnew
Each year, Virginia Tech produces the Global Agricultural Productivity (GAP) Report, which provides a snapshot of the current state of agriculture and a projection of its future. Tom and Jessica, executive editor and managing editor, respectively, of the report, joined the podcast just prior to the 2023 release to explain what it is and how they hope it's used.
Date: Oct 01, 2023 - -
General ItemThe Metaverse, Digital Twins, and Green AI with Walid Saad
Walid Saad fields questions about the metaverse, digital twins, and artificial intelligence’s potential impact on the environment.
Date: Sep 24, 2023 - -
General ItemSemiconductors, Packaging, and more with Christina Dimarino
Christina Dimarino chats about semiconductors, the importance of packaging in onshoring their production, and what Virginia Tech is doing to excel workforce development in this field.
Date: Sep 15, 2023 - -
General ItemPilot: Electric Vehicles with Hesham Rakha
Hesham Rakha shares insights on what sustainable mobility means, the gas price at which electric vehicles becomes the more cost effective option, and some of his personal experiences with an electric car.
Date: Aug 14, 2023 -